IMMUNE : Benefits
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Leapfrog IMMUNE is a supplement containing lactoferrin, zinc and vitamin C. Think of it as your own body’s elite squad that you call in when you need extra immune support against viruses and bacteria. Taking Leapfrog IMMUNE at the beginning of a cold – and we all know how those play out – may help to reduce and shorten symptoms.
Every dose of Leapfrog IMMUNE contains 250mg of lactoferrin and the recommended daily intake of zinc and vitamin C (within two tablets). These actives work together to support the body’s own immune function. When our immune system has been compromised, Leapfrog IMMUNE is absorbed through receptors in the mouth and gastrointestinal tract, beginning a reaction between cells that ultimately activates genes; these produce mediators that circulate in the blood and raise our body’s immune defences.
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Lactoferrin is found in the milk of most mammals as one of the vital ingredients that primes a baby’s immune system (lacto means milk, and ferrin means iron). An iron-binding protein, lactoferrin exists in all your bodily secretions to combat environmental toxins when they enter the body. The largest storage of lactoferrin is in neutrophils, a type of white blood cell. They burst open and release lactoferrin to prevent the spread of infection. Lactoferrin helps maintain immune homeostasis or balance. It helps to regulate our body, so we have normal, healthy ranges for things like temperature, energy intake and growth. Lactoferrin also supports digestive and gut health, promoting prebiotic activity.
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Separating lactoferrin from milk is a complicated endeavour and we chose the Proferrin® brand of lactoferrin as it offers the highest purity on the market (>95%). The lactoferrin is extracted from premium fresh milk – not colostrum or the by-product whey – and the milk is produced in a dynamic dairy production area in Northern France. In order to exercise its immune bioactivity, bovine lactoferrin needs to be native. A process involving low temperature and gentle chromatography and filtration preserves the native structure of Proferrin®, so it’s just as you would find in fresh milk.
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There are approximately 9,500 articles on PubMed, a site for peer-reviewed medical research and studies, that discuss the activity of milk (bovine) lactoferrin. On the Science page, we have highlighted a few of the studies that relate to lactoferrin’s support of immune function and the associated human trials.
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Lactoferrin is already present within the body, so Leapfrog IMMUNE works in synergy with our bodies’ own natural immune systems. Adding the zinc and vitamin C gives Leapfrog IMMUNE a power punch of immune support.
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Do consult your healthcare practitioner before taking this product if any of the following apply to you:
You suffer from severe asthma, autoimmune or allergic conditions (lactoferrin levels in the body are elevated in the conditions of lymphocytic leukemia or pancreatitis), you suffer from milk protein allergies or you take blood thinning medications.
SNOOZE : Benefits
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Leapfrog SNOOZE is a supplement containing Lactium®, lactoferrin and vitamin B6. Think of the calm state of a baby after feeding…Leapfrog SNOOZE is formulated to emulate that mood, promoting relaxation and more restful sleep. Taking Leapfrog SNOOZE during periods of anxiety or sleep disturbance may help to calm and unwind the mind.
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Lactium® is a natural milk protein hydrolysate that was created by French scientists to emulate the calm mood of a baby after feeding. The enzymes present in a baby’s digestive system help to release a bioactive peptide that induces a state of bliss. As our digestive system matures our digestive enzymatic system is no longer able to release the peptide and we lose the benefit.
French researchers developed an innovative process to reproduce a baby’s digestive mechanism. They used a well-known digestive enzyme – trypsin – to isolate the milk protein hydrolysate containing the bioactive peptide – alpha-casozepine – from casein. It has a gentle action on the body but has been clinically proven to reduce stress-related symptoms and encourage better sleep.
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Alpha-casozepine is a bioactive decapeptide – originating from S1 casein, a cow’s milk protein – that has an affinity for gamma-aminobutyric acid (GABA) receptors in the brain. Scientific evidence suggests it has an anxiolytic (anxiety-reducing) effect similar to benzodiazepines, but without the side effects.
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By having an affinity for certain receptors in the central nervous system called GABAA receptors, Lactium® increases the activity of Gamma-Aminobutyric acid (GABA), a neurotransmitter, or chemical messenger, that is well known for its inhibitory action on anxiety and its relaxing properties.
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Cortisol is a stress hormone produced in the adrenal glands that helps engage your “fight or flight” response and contributes to maintain your energy balance during all day. It also acts as a vital part of your circadian rhythm, reaching a peak in the morning and reducing to minimum at around midnight. The peak in the morning gives us energy, and the reduction by the evening leads to tiredness.
If there is an acute stress, the body will return to baseline. But if the stress is too frequent or chronic, then the body cannot recover and regenerate resources, leading to health problems such as weight increase, sleep disorders, and immune system dysregulation.
Lactium® has been shown to have an effect on cortisol relase; blood cortisol levels reduce significantly after an acute stress event when supplementing with Lactium®. Even with chronic anxiety, Lactium® reduces blood cortisol level in the morning.
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There have been 9 rigorous clinical studies conducted between 1999 and 2021 on more than 500 adult volunteers that have proven the effectiveness of Lactium®. On the Science page, we have highlighted a few of the studies that relate to Lactium®’s effects on stress and sleep disturbance and the associated human trials.
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Lactium®is a natural and patented ingredient made from the casein in milk – Mother Nature’s most extraordinary cocktail for health and wellness. Unlike benzodiazepines – a type of sedative medication – Lactium®isn’t addictive, even at a high dosage, nor does it have any other side effects such as disinhibition.
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There are no specific contraindications concerning Lactium®, though do consult your healthcare practitioner before taking this product if you have any concerns.
For those with lactose intolerance, Lactium® contains about 0.6% lactose, so one dose of 150 mg Lactium® per day amounts to 0.9 mg of lactose.
Caffeine reduces the release of GABA and so can decrease the effectiveness of Lactium®.
IMMUNE : Practice
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S.O.S
You’ve felt that first tickle in the throat or drip in the nose. You’re thinking “Nooooo!”
These are the warning signs and you know how this plays out.
This is the moment to take Leapfrog IMMUNE for a surge of immune support.
Take two tablets per day – morning and evening, with or without food.
Continue until you feel yourself again, which could be between one and five days.
Panic over.
Pulse Method™
You admit you’re not eating or sleeping properly, and you’re stressed out and under-exercised.
Perhaps you’re not as young and robust as you once were.
It’s the snotty season and you want to safeguard yourself.
Take Leapfrog IMMUNE by pulse method™ to maintain continual immune support over time.
Simply put, it’s one chewable tablet per day – one month on, one month off – over a season.
In winter, for example, that’s one tablet per day for the months of October, December and February (check out our Winter Bundle that will have you covered).
If we eat well, sleep well, exercise and are stress-free, then the body can be brilliant at fighting viruses and bacteria. Consider Leapfrog IMMUNE your backup.
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We suggest one chewable tablet in the morning and one in the evening, as it’s easy to remember.
Or, one chewable tablet per day if desired.
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During an infectious episode, you can expect to take between 1 to 10 chewable tablets over the course of 1 to 5 (two chewable tablets per day).
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Owing to the number of viruses and bacteria and their various reactions in different people, it’s difficult to predict.Studieshave shown that taking lactoferrin during a cold can reduce the symptoms, and Leapfrog IMMUNE may safeguard you from further infections once your immune system is compromised.
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During the gentle manufacturing process, the lactose in lactoferrin is reduced to very low levels. The lactose content in our lactoferrin is typically 0.01% – virtually lactose-free – but, as milk is an allergen, do have a chat with your health practitioner if you have any concerns.
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No, Leapfrog's lactoferrin is sourced from milk and therefore not suitable for those with a milk allergy.
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Lactoferrin is only found in small amounts in milk – the mean concentration is around 100mg/litre. It can also be assumed that most of the bovine lactoferrin (bLf) in milk foods and drinks is denatured through the sterilization and pasteurization of dairy products.
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Yes, and it is manufactured in a nut free facility.
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Yes.
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Yes.
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No. Lactoferrin is a cow’s milk protein and therefore this product is unsuitable for vegans.
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Yes. Lactoferrin has been shown to effectively treat iron deficiency anaemia in pregnant women without the gastrointestinal side effects of high dose iron supplements. If you have any concerns, however, do consult a physician before taking this supplement.
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Lactoferrin is safe for children to take (and is, of course, a key component of mother’s milk), so we suggest our chewable tablets are suitable from age 4. Our formula contains the recommended daily amount of zinc and vitamin C for children (aged 4-11) in 1 tablet, and for adults in 2 tablets.
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We’ve designed the packaging to be light and transportable, so you can pop a chewable tablet out of the blister pack the moment you need an immune boost.
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Yes, yes, yes – this is a perfect opportunity to support your body’s immune system. An airplane is a petri dish for germs to thrive in: close proximity of passengers, frequent passenger turnaround and recirculated air. Think of tray tables, belt buckles and seat pockets as germ magnets, so take some sanitizing wipes and chew your Leapfrog IMMUNE.
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Please see the blister pack or the back of the carton for the Best Before End Date. Please keep Leapfrog IMMUNE in a cool, dry place. Unlike frogs, our chewable tablets should not get wet.
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One of the reasons Lactoferrin is so successful as an anti-viral and anti-bacterial is that it binds iron to itself, iron that viruses and bacteria need to survive and thrive. Lactoferrin can help to starve the viruses/bacteria of their food source, giving the body a chance to mobilise itself against infection. The only issue might be if you have hemochromatosis as Lactoferrin raises serum iron and ferritin (but it’s a natural way to up iron levels during anaemia, without side effects). If you have any health issues in this area, do consult with your health practitioner first before taking this product.
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No.
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There are no contraindications in taking Lactoferrin every day over a long period, although there is as yet no data for supplementing with it one’s whole life.
Of course, it is important to speak to your doctor before beginning any supplement. However, if intending on a long term supplementation with Lactoferrin it would be an idea to take some breaks, for example during the summer period with less infection, so you rely on a ”natural immune system” without a perpetual booster. This was the thinking behind Leapfrog’s “Pulse Method”.
SNOOZE : Practice
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S.O.S
Feeling frazzled or have a stressful event on the horizon? Chew one tablet per day as needed, two tablets per day for up to thirty days, or four tablets per day for two days (one day before, and the day of the stressful event). For children aged 7-14, chew one tablet per day as needed.
Night Night
If you’re looking for some quality Zzzzz, then chew one to two tablets one hour before bed. For children 7-14 years, chew one tablet one hour before bed. Not suitable for children under 7 years old.
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Those suffering from severe lactose intolerance may often consume 7 to 12 g of lactose per day.
Lactium® contains about 0.6% lactose.
One dose of 150 mg Lactium® per day – the amount in one tablet of Leapfrog SNOOZE – corresponds to 0.9 mg of lactose.
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No, Leapfrog's Lactium ingredient is sourced from milk and therefore not suitable for those with a milk allergy.
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Yes, and it is manufactured in a nut free facility.
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Yes.
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Yes.
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No. Lactium® is a cow’s milk protein hydrolysate and therefore this product is unsuitable for vegans.
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Yes. Lactium® is safe for pregnant women.
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Lactium® is of natural origin and can be used at all ages, even by children. Each Leapfrog SNOOZE tablet contains 150mg which is suitable from age 7. Our formula contains lactoferrin (50mg – a suitable amount for children of all ages) and the recommended daily amount of vitamin B6 for children aged 7 and up in 1 tablet.
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Lactium® can be used before a sporting competition to better manage tension and aid sleep and concentration, as well as after the event to help the body recover. It is not listed as a forbidden substance by the World Anti-Doping Agency.
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Please see the blister pack or the back of the carton for the Best Before End Date. Please keep Leapfrog SNOOZE in a cool, dry place. Unlike frogs, our chewable tablets should not get wet.
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Lactium® is an ingredient of natural origin as it is sourced from milk, and is harmless. Unlike benzodiazepines, which belong to the anxiolytics family, Lactium®does not create any addiction, even at a high dosage.
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The decapeptide with the soothing properties found in Lactium® – namely alpha-casozepine – is not present by itself in milk and is encrypted in AS1- casein. It’s released in neonates but not in adults. The enzymatic system in adults is more complex and can’t allow the quantitative delivery of this specific sequence from the protein.
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Randomized, double-blind, placebo-controlled trials have been run, details of which can be found on our dedicated Lactium® webpage. Clinical studies were made according to Good Clinical Practice Guidelines with official ethical committees. In the human trials, tests were used that have been validated by the scientific community (i.e. Stroop test, Cold pressor test, Spielberger questionnaires,…). They were not developed specifically for these studies. Blood pressure reactivity to stress (systolic and diastolic blood pressure) was also tested, as well as ACTH and cortisol which are stress-related hormones. They are validated physiological markers of stress. Find more case studies here.
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The recommendation is for 150mg per day, equivalent to one Leapfrog SNOOZE tablet (for age 7 and above). This dosage can be increased for special situations that induce additional stress (like an exam, presentation or important meeting.
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During the various clinical studies in humans, Lactium® was taken either in the morning or in the evening. In both cases, the efficacy of Lactium® to reduce stress was observed. In order to alleviate stress prior to sleep, Lactium® can be taken one hour before bedtime. In animal studies, Though Lactium® has been shown to be physiologically effective about 1 hour after intake, a regular sensation of well-being can take effect between one week to 15 days. Lactium® helps to regulate stress and stress symptoms, but the perceived effect may be different from one situation to another, depending on the level of stress and the individual.
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In animal studies, Lactium®’s effect begins to decrease about 6 hours after intake. In humans, the sensation of well-being has been shown to last after stopping the supplement treatment. Lactium is quickly metabolized without accumulating effect. There is no remanence effect with Lactium when we stop the supplementation.
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Studies have been conducted on Lactium® to determine the bioactive peptide structure (such as NMR, molecular dynamics simulation, circular dichroism). The peptide adopts an alpha-helix structure with both lipophilic and hydrophilic faces. Because of its amphipathic structure, the bioactive peptide is likely to pass through the intestinal barrier. The mechanism of action of Lactium® is complex, but the effect induced by Lactium® on stress requires the message to come to the brain. In vitro studies show that the bioactive peptide contained in Lactium® has an affinity for non-peripheral-type GABAA receptors, receptors that are commonly involved in anxiolysis. Sequence homology with DBI (diazepam binding inhibitor), an endogenous ligand of the GABAA receptor, and structural homology with benzodiazepines has been demonstrated.
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In our studies, we see an effect of Lactium after 15 days of supplementation. We have no data after one day of supplementation (for 150mg and 300 mg), but for 600mg of supplementation of Lactium, there’s an effect after 2 days.
IMMUNE : Formula
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All of our ingredients are generally regarded as safe (GRAS) by the EFSA (the European Food Safety Authority)
Leapfrog IMMUNE contains Proferrin® – a high-quality, native and pure lactoferrin produced in France from premium fresh cow’s milk. It strengthens the immune system and digestive health and has a positive effect on innate and adaptive immune responses through the stimulation of immune cells.
Leapfrog IMMUNE contains zinc, an essential nutrient that performs many vital roles in the body. One of the critical benefits of this mineral is its support of the development and function of immune cells, which is why you’ll find zinc in natural cold treatments. We’ve chosen zinc citrate, which is well absorbed by the body.
Leapfrog IMMUNE also contains vitamin C – a strong antioxidant which is widely thought to strengthen your body’s natural defences. Antioxidants protect cells from harmful molecules (free radicals) and thereby support the immune system. It also helps encourage the production of certain white blood cells that protect against infection. Our vitamin C is a blend of ascorbic acid and calcium ascorbate which are effective forms for the body.
Leapfrog IMMUNE contains some other necessary agents, which are all safe ingredients:
Xylitol – a substitute for table sugar, xylitol is regarded as a healthy alternative to traditional sweeteners that has a low glycemic index. It has antibacterial and anti-inflammatory potential and has a significant antiplaque effect on the teeth surface and can reduce gingival inflammation.
Isomalt – a sugar-free sweetener that doesn’t increase blood glucose or insulin levels and is safe for teeth. It has been shown to promote good bacteria in the gut, and it acts as a texturizing agent for the tablets.
Citric Acid – this boosts the acidity, enhances the flavour, and stabilises and preserves the active ingredients in our chewable tablets.
Natural Flavourings – we’ve chosen lemon and orange flavours to give our chewable tablets a pleasant tang.
Magnesium stearate – this is a flow agent which allows the chewable tablet to hold its shape. Magnesium is an essential mineral and stearic acid is a saturated fatty acid found in many foods such as eggs, coconut oil, chicken, walnuts and salmon. Both are entirely safe, and magnesium stearate is simply a salt that combines them both.
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This product has been formulated with no known counter indications/interactions between the ingredients included. Lactoferrin has European Food Safety Authority and FDA approval as safe (GRAS) and our dosage is well within the specified daily limit of 3g per day within foods for medical purposes. Our lactoferrin is 100% natural, however, if you are taking any medications, it’s best to check with your doctor first before taking Leapfrog IMMUNE.
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Our lactoferrin comes from milk produced by French cows that live on family farms. The farms are all prohibited from the use of hormones and are routinely checked by veterinary experts.
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There are no known contra-indications with other supplements, however if you have any concerns do chat with your healthcare practitioner first.
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Apo lactoferrin is lactoferrin without iron (unsaturated) and Holo lactoferrin is lactoferrin saturated in iron. To obtain both apo and holo lactoferrin, a chemical process is needed. Our lactoferrin is neither apo nor holo as it is native: no chemical process is involved during the process. It’s as native as the lactoferrin in our body and efficient as it is.
SNOOZE : Formula
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All of our ingredients are generally regarded as safe (GRAS) by the EFSA (the European Food Safety Authority)
Leapfrog SNOOZE contains Lactium® – a patented milk protein hydrolysate produced in France from premium fresh cow’s milk. It contains a peptide that has an affinity for the GABAA receptor and can reduce cortisol levels. As such it has calming properties and can promote restful sleep.
Leapfrog SNOOZE contains Proferrin® – a high-quality, native and pure lactoferrin produced in France from premium fresh cow’s milk. It strengthens the immune system and digestive health and has a positive effect on innate and adaptive immune responses through the stimulation of immune cells.
Leapfrog SNOOZE contains vitamin B6, an essential, water soluble vitamin that supports mood regulation and shows key benefits to the brain and nervous system. B6 aids in the production of melatonin, the precursor to sleep and has a key role in supporting sleep/wake cycles. We’ve chosen Pyridoxal 5-Phosphate (P5P) which is the bioactive, more absorbable form of B6 and so doesn’t need to be converted within the body.
Leapfrog SNOOZE contains some other necessary agents, which are all safe ingredients:
Xylitol – a substitute for table sugar, xylitol is regarded as a healthy alternative to traditional sweeteners that has a low glycemic index. It has antibacterial and anti-inflammatory potential and has a significant antiplaque effect on the teeth surface and can reduce gingival inflammation.
Isomalt – a sugar-free sweetener that doesn’t increase blood glucose or insulin levels and is safe for teeth. It has been shown to promote good bacteria in the gut, and it acts as a texturizing agent for the tablets.
Citric Acid – this boosts the acidity, enhances the flavour, and stabilises and preserves the active ingredients in our chewable tablets.
Natural Flavourings – we’ve chosen berry flavour to give our chewable tablets a pleasant taste.
Red Beet Juice Extract – Lactium®, the primary ingredient of Leapfrog SNOOZE is cream in colour and so we added red beet juice extract to give the tablets a pale purple colour to match the natural berry taste.
Magnesium stearate – this is a lubricant which stops the formulation from sticking as its made and allows the chewable tablet to hold its shape. Magnesium is an essential mineral and stearic acid is a saturated fatty acid found in many foods such as eggs, coconut oil, chicken, walnuts and salmon. Both are entirely safe, and magnesium stearate is simply a salt that combines them both.
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This product has been formulated with no known counter-indications/interactions between the ingredients included. Lactium® and Lactoferrin have European Food Safety Authority and FDA approval as safe (GRAS) and our dosages are well within the specified daily limits within foods for medical purposes.Lactium® has been consumed for more than 15 years throughout the world, especially in Asia, without resulting in any reports specifically related tolactose or its dairy origin.Our Lactium® and lactoferrin are 100% natural, however, if you are taking any medications, it’s best to check with your doctor first before taking Leapfrog IMMUNE.
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OurLactium® andlactoferrin come from milk produced by French cows that live on family farms. The farms are all prohibited from the use of hormones and are routinely checked by veterinary experts.
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There are no known contra-indications with other supplements, however if you have any concerns do chat with your healthcare practitioner first.
Ethics
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Leapfrog Remedies’ products are formulated by scientists and compounding pharmacists who research, trial and test ingredients for a wide range of supplements.
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Leapfrog Remedies supplements are manufactured in the UK by a supplement company that has BRCGS ‘AA’ Food Safety Accreditation – all their products comply with UK and EU legislation – so this isn’t their first rodeo.
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The zinc and vitamin C are sourced from the UK, and the Lactium® and lactoferrin from France.
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The majority of the carbon impact of milk comes from other components, such as cream and lactose. Because it is such a small fraction of the milk, the calculation of the carbon impact of our lactoferrin production is 0.94 kg of CO2 / kg of lactoferrin. In other terms, one kilogram of lactoferrin is the equivalent of 1kWh of electricity – and that makes 4000 Leapfrog IMMUNE chewable tablets.
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Leapfrog Remedies contributes to Ecologi, an environmental charity that is certified B Corps. Every month we support two different impact driven climate projects, from generating clean electriticty from hydropower in India to protecting lowland peat forest in Indonesia. Ecologi also plants trees every month on our behalf.
Shopping
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Details will be sent to you when your order is shipped. Your order will be shipped the same day if the order is placed before 1pm on a weekday. Orders placed on a Saturday will be shipped on the following Monday.
You can also log in to your account if you created one to see the status of your order.
If your order doesn’t arrive please email hello@leapfrogremedies.com and we will look into it for you.
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Next-day delivery orders need to be placed before 1pm to be shipped the same day otherwise they will be shipped the following working day. If you place an order on a Friday after 1pm it will be shipped on the following Monday (subject to bank holidays).
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If you’re after a refund (hey, we all have the right to change our minds), then send it back to us in its original packaging with all the accompanying material within 30 days of purchase. It must be unopened and unused, and in the same condition that you received it.
We can’t accept any product back that has been opened or used.
Our address is:
Leapfrog Remedies Ltd, Suite 106, 264 Lavender Hill, London SW11 1LJ
The shipping costs are the responsibility of the customer and are non-refundable.
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We’re so sorry to hear this, no one wants to receive a dud product. Get in touch by emailing us at hello@leapfrogremedies.com with a few photos of the problem area, and we will either refund you or send you new product.
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Just email us at hello@leapfrogremedies.com and we’ll be happy to resolve it.
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We’re so glad you took the leap and loved it! Leave a review for IMMUNE on the product page here or for SNOOZE here, or share and tag us on Instagram or Facebook @leapfrogremedies
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Just click the ‘unsubscribe’ button at the bottom of our email – and it’s bye bye from us. 🙁
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As a fledgling supplement brand we’re so happy to hear you’re interested in sharing the Leapfrog love! Send us an email at hello@leapfrogremedies.com and we’ll be in touch quicker than you can jump from one lily pad to another!